The Santo Domingo el Antiguo Altarpiece is a 1577-1579 altarpiece by El Greco, painted for the Monastery of Santo Domingo el Antiguo in Toledo, Spain. The artist had just arrived in Spain and this was his first major commission there, gained thanks to Diego de Castilla, who he had met in Rome.
The total commission was for nine canvases, seven for the high altar and two for side altars. The high altarpiece was made up of an upper main canvas , a lower main canvas , four flanking panels of saints and a small painting on the tympanum between the two main paintings . Of these, only the original panels of St John the Baptist and St John the Evangelist remain in situ, along with the painting for the right-hand side altarpiece, Resurrection. Assumption is now in the Art Institute of Chicago and Holy Trinity in the Prado Museum. The rest are replaced in the church by copies.
