Manchester Jewish Museum occupies the former Spanish and Portuguese Synagogue on Cheetham Hill Road in Manchester, England. It is a grade II* listed building.The synagogue was completed in 1874 but the building became redundant through the migration of the Jewish population away from the Cheetham area further north to Prestwich and Whitefield.
It re-opened as a museum in March 1984 telling the story of the history of Jewish settlement in Manchester and its community over the last 200 years.