Palazzo Labia is a baroque palace in Venice, Italy. Built in the 17th–18th century, it is one of the last great palazzi of Venice. Little known outside of Italy, it is most notable for the remarkable frescoed ballroom painted 1746–47 by Giovanni Battista Tiepolo, with decorative works in trompe l'oeil by Gerolamo Mengozzi-Colonna.
In a city often likened to a cardboard film set, the Palazzo is unusual by having not only a formal front along the Grand Canal, but also a visible and formal facade at its rear, and decorated side as well, along the Cannaregio Canal. In Venice, such design is very rare. The palazzo was designed by the architect Andrea Cominelli , the principal facade is on the Cannaregio Canal; a lesser three bayed facade faces the Grand Canal. A later facade probably designed by Giorgio Massari is approached from the Campo San Geremia.