Greyfriars, Worcester is a Grade I listed building in Worcester, England. Its location near to a former friary of the Franciscan order of Greyfriars has in the past led to speculation that it was constructed as their guest house, but it is now believed to have been built as a house and brew-house c.1485 for Thomas Grene, brewer and High Bailiff of Worcester from 1493-1497. It has been in the ownership of the National Trust since 1966.