Cleveland , officially the City of Cleveland, is a major city in the U.S. state of Ohio, and the county seat of Cuyahoga County. It is located on the southern shore of Lake Erie, across the U.S. maritime border with Canada and approximately 60 miles west of the Ohio-Pennsylvania state border. Cleveland is the largest city on the shores of Lake Erie and the largest metropolitan economy and population in Ohio. Metropolitan Cleveland, with a population of 2.8 million, comprises two US-defined metropolitan statistical areas , the Cleveland MSA and the Akron MSA. Its GDP is $171 Billion , making it the 21st largest in the United States. The city proper, with an estimated estimated 2019 population of 381,009, ranks 53rd-largest city in the United States, though its economy and population are fluid across individual municipal boundaries.Designated as a "Gamma -" global city by the Globalization and World Cities Research Network, Cleveland anchors the Cleveland–Akron–Canton Combined Statistical Area, the most populous combined statistical area in Ohio and the 15th largest in the U.S., with a population of 3,515,646 in 2010. Cleveland was founded in 1796 near the mouth of the Cuyahoga River by General Moses Cleaveland, after whom the city was named. A port city, it grew into a major manufacturing center due to its location on both the river and the lake shore, as well as numerous canals and railroad lines. Cleveland's economy relies on diversified sectors such as manufacturing, financial services, healthcare, biomedicals, and higher education.The city's major cultural institutions include the Cleveland Museum of Art, the Cleveland Museum of Natural History, the Cleveland Orchestra, Playhouse Square, and the Rock and Roll Hall of Fame. Known as "The Forest City" among many other nicknames, Cleveland serves as the center of the Cleveland Metroparks nature reserve system.